On December 4–5, 2009, in Monte Carlo, Monaco, the International Society for Fracture Repair (ISFR) held its first 2-day combined event, “Osteoporosis: from Evidence to Action”, endorsed by the International Osteoporosis Foundation (IOF). The initiative united research and educational fronts, comprising working groups followed by symposia. The Osteoporotic Fracture Campaign (OFC) was launched by Professor Antonio Moroni (Bologna University, Bologna, Italy) in 2002 at the “Fracture Treatment in Elderly and Osteoporotic Patients” symposium (Rizzoli Orthopaedic Institute, Bologna, Italy, May 16–18), and was subsequently officially adopted by the umbrella organization of the ISFR. The OFC has evolved rapidly over the 7 years since its inception, beginning with workshops and brainstorming think-tanks gathering together experts to discuss “burning issues” in the field, and progressing to working groups seeking to improve outcomes [1,2]. Osteoporosis: from Evidence to Action was the product of synthesis of research stemming from previously held workshops, with international faculty presenting on >50 topics covering all aspects of osteoporosis, from patient management strategies to surgical treatments and outcome assessment. The success of the innovative working groups pivoted around the skills and multispecialty expertise evident in the osteoporosis network, ranging from geriatricians to engineers, working in a collaborative fashion with industry partners on the fundamentals of science and methodology of trial designs. The primary goals of the event were as follows: