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Risk – Recurrence or Contralateral Disease

Kirova YM, Savignoni A, Sigal-Zafrani B et al.

Institut Curie, Paris, France.

 Breast Cancer Res Treat 2010;120:119–26.

Editor’s note: Several studies have suggested that BRCA gene mutations might influence the response to radiation therapy, because tumors in BRCA1/2 carriers are more sensitive to ionizing radiation. The current authors investigated whether BRCA mutation status influences the rate of ipsilateral tumor development after breast-conservation therapy (BCT).

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