Chaitman BR, Hardison RM, Adler D et al.; BARI 2D study group.
St Louis University, St Louis, MO, USA.
Circulation 2009;120:2529–40.
Editor’s note: It well recognized that vasculopathy in patients with type 2 diabetes mellitus differs from that occurring in patients without diabetes (
Coron Artery Dis2010;21:189–98). Retrospective analysis of the results of the initial BARI (Bypass Angioplasty Revascularization Investigation) trial led investigators to conclude that the then available coronary intervention (percutaneous transluminal coronary angioplasty) increased mortality rates in patients with diabetes who were being treated for unstable coronary artery disease (CAD) compared with those without diabetes (
N Engl J Med 1996;335:217–25). Even with contemporary therapy such as primary percutaneous coronary intervention (PCI) using drug-eluting or bare-metal stents, results in patients with diabetes and acute coronary syndrome (ACS) are less favorable than in ACS patients without diabetes (
Coron Artery Dis 2010;21:189–98).