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Prognosis

Kopetz S, Hoff PM, Morris JS et al.

University of Texas MD Anderson Cancer Center, Houston, TX, USA.

 J Clin Oncol 2010;28:453–9.

Editor’s note: In this study, Kopetz et al. recorded changes in the levels of several circulating cytokines and angiogenic factors in 43 patients with metastatic colorectal cancer following treatment with infused fluorouracil, leucovorin, irinotecan, and bevacizumab. Some markers, notably interleukin-8 (IL-8), were found to be prognostic for progression-free survival (PFS), and some were found at altered levels prior to disease progression.

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