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CF Lung Disease

Pillarisetti N, Williamson E, Linnane B et al.; Australian Respiratory Early Surveillance Team for Cystic Fibrosis.

Royal Children’s Hospital Melbourne, Parkville, VIC, Australia.

 Am J Respir Crit Care Med 2011;184:75–81.

Editor’s note: Lung function is reduced in infants with cystic fibrosis (CF) shortly after diagnosis in both populations with and those without the benefit of newborn screening. In this article, the authors present longitudinal data from a cohort in which 28 of 37 patients were diagnosed by newborn screening. In this cohort, they investigated the relationship between the evolution of lung function over time and the occurrence of pulmonary inflammation and infection.

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