Diedrichs H, Pfister R, Hagemeister J et al.
University of Köln, Cologne, Germany.
Diabet Med 2008;25:228–31.
Editor’s note: The impact of diabetes and hyperglycemia on cardiovascular risk has been well documented and it is believed patients with diabetes are at a significant increased risk of restenosis of coronary vasculature following intervention. The authors of the present article analyzed the risk of restenosis based upon achieved hyperglycemia following intervention. The study included patients without diabetes who were not receiving any specific glycemic therapy, with a glycated hemoglobin (HbA
1c) level of <6.4% and a fasting glucose level of <7 mmol/L. Of 101 patients studied, approximately 60% did not have restenosis and of the remaining patients with restenosis, the single most powerful metabolic indicator of risk was HbA
1c (particularly if the HbA
1c levels had increased, which gave an odds ratio of 3 for restenosis).