Salinari S, Bertuzzi A, Asnaghi S et al.
University of Rome La Sapienza, Rome, Italy.
Diabetes Care 2009;32:375–80.
Editor’s note: In this article, the mechanisms and details relating to the improvement in glucose metabolism seen after bariatric surgery are explored. The study involved nine morbidly obese type 2 diabetes patients with a mean body mass index (BMI) of 51.7 kg/m
2, who underwent biliopancreatic diversion, as well as six sex- and age-matched healthy controls with a mean BMI of 24.6 kg/m
2. Insulin sensitivity and
β cell function were assessed by means of intravenous (IVGTT) or oral glucose tolerance testing (OGTT) before and 1 month after surgery in all patients.