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Hepatology

Galbois A, Thabut D, Tazi KA et al.

Hôpital Beaujon, Clichy, France.

 Hepatology 2009;49:175–84.

[2] Serum and ascitic fluid bacterial DNA: a new independent prognostic factor in noninfected patients with cirrhosis.

Zapater P, Francés R, González-Navajas JM et al.

Universidad Miguel Hernández, Alicante, Spain.

 Hepatology 2008;48:1924–31.

Editor’s note: Infection is a complication of decompensated cirrhosis, and the release of cytokines can cause a worsening of liver function (Liver Int 2004;24:437–45). In the first article, the authors evaluated ex vivo exposure to high-density lipoprotein (HDL) during the inflammatory response induced by lipopolysaccharide (LPS) [1]. HDL can neutralize LPS; as patients with cirrhosis have lower concentrations of HDL (Eur J Clin Invest 1995;25:143–8), this may be relevant to susceptibility and response to infection.

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