Paper of the Month - May, 2011

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Carbonic anhydrase IX and pathological features as predictors of outcome in patients with metastatic clear-cell renal cell carcinoma receiving vascular endothelial growth factor-targeted

Choueiri TK, Regan MM, Rosenberg JE et al.
Carbonic anhydrase IX (CAIX) is a cytosolic transmembrane protein implicated in regulating cell pro-liferation in response to hypoxia. CAIX is expressed in the vast majority of renal clear-cell carcinomas (RCC).


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