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Diagnosis and Staging

Park JW, Jo MK, Lee HM.

Samsung Medical Center, Seoul, Korea.

 BJU Int 2009;103:615–9.

Editor’s note: Disease stage is the strongest predictor of outcome for patients with renal cell carcinoma (RCC). Approximately 30–35% of patients with RCC have localized disease at the time of diagnosis (Cancer Treat Rev 2007;33:1–8). A complete recovery is possible at this disease stage through radical nephrectomy. Owing to the frequently indolent course of the disease, surgical treatment of the metastases in advanced disease can improve the clinical outcome. Thus, early identification of the primary tumor or metastases can slow or prevent the development of the disease. The imaging methods commonly used for follow-up after radical nephrectomy include magnetic resonance imaging and bone scan to discover any new sites of disease. The role of positron-emission tomography (PET) in the staging of RCC is currently unclear owing to the discordant results published by different groups of investigators concerning the efficacy of PET for the identification the renal tumors and metastases.

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