Paper of the Month - Volume 20 Issue 1

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Hodgkin Lymphoma

Eichenauer DA, Fuchs M, Pluetschow A et al.

University Hospital of Cologne, Cologne, Germany.

 Blood 2011;118:4363–5.

[2] Treating limited-stage nodular lymphocyte predominant Hodgkin lymphoma similarly to classical Hodgkin lymphoma with ABVD may improve outcome.

Savage KJ, Skinnider B, Al-Mansour M et al.

University of British Columbia, Vancouver, BC, Canada.

 Blood 2011;118:4585–90.

Editor’s note: Nodular lymphocyte-predominant Hodgkin lymphoma (nlpHL) is relatively rare, accounting for approximately 5% of all HL cases. This entity is characterized by an indolent clinical course and typically confers an excellent long-term prognosis, particularly in the majority of cases with limited-stage nlpHL. Up to now, the standard treatment for limited-stage disease has been radiotherapy (RT) and/or chemotherapy. In contrast to classical HL, malignant nlpHL cells consistently express high levels of CD20. Two studies of nlpHL are discussed herein.



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