In vivo imaging of cortical pathology in multiple sclerosis using ultra-high field MRI.
Mainero C, Benner T, Radding A et al.
Editor’s note: Detection of cortical lesions using the currently available magnetic resonance imaging (MRI) methods is limited due to technical reasons and because of specific properties of the lesions themselves, such as the low inflammatory cell infiltration and the low myelin density in the external cortical layers. Ultra-high field scanners, including those with a magnetic field strength of 7 Tesla (T), improve image resolution, contrast, and signal-to-noise ratio, which subsequently enhance detection of cortical lesions.