Switching multiple sclerosis patients with breakthrough disease to second-line therapy.
Castillo-Trivino T, Mowry EM, Gajofatto A et al.
University of California, San Francisco, San Francisco, CA, USA.
Castillo-Trivino and colleagues present a retrospective cohort study based on 993 patients with multiple sclerosis (MS) seen at the University of California, San Francisco MS Center (CA, USA). The study investigated the relapse rates seen with three treatment strategies for the 95 patients in this group who had experienced breakthrough disease on first-line therapy: