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Imaging

Walter U, Wagner S, Horowski S et al.

University of Rostock, Rostock, Germany.

 Neurology 2009;73:1010–7.

Editor’s note: Transcranial sonography has demonstrated hyperechogenic lesions of basal ganglia in different primary neurodegenerative disorders (Lancet Neurol 2008;7:1044–55). Such subcortical gray matter hyperechogenicity is thought to derive from trace metal deposition. Current pathophysiological concepts consider multiple sclerosis (MS) to feature both inflammatory and neurodegenerative aspects.

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