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Prognosis

Deloire MS, Ruet A, Hamel D et al.

INSERM U 1049, University Victor Segalen, Bordeaux Cedex, France.

 Neurology 2011;76:1161–7.

Editor’s note: In a previous study performed by the same authors, cognitive impairment at baseline was found to be associated with magnetic resonance (MR) parameters evaluating diffuse brain damage (J Neurol Neurosurg Psychiatry 2005;76:519–26). The aim of the present study was to establish whether diffuse brain damage outside of lesions, and their changes over 2 years, predicted the deterioration of cognitive performance over a 7-year period.

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