Lewis GD, Murphy RM, Shah RV et al.
Harvard Medical School, Boston, USA.
Circ Heart Fail 2011;4:276–85.
Editor’s note: Pulmonary hypertension (PH) in association with left ventricular (LV) systolic dysfunction, otherwise known as pulmonary venous hypertension (PVH), is common and a poor prognostic indicator. This study expands on prior observations by analyzing the change in pulmonary artery pressure (PAP) during exercise in this patient population. Sixty patients, generally with New York Heart Association (NYHA) II/III LV failure (mean LV ejection fraction 31%) underwent simultaneous cardiopulmonary exercise testing and PA catheterization and were compared with 19 age- and sex-matched controls.