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Systemic Lupus Erythematosus Treatment: A Guide to Photoprotection

Nicole Fett, MD, and Victoria P Werth, MD

Ultraviolet radiation (UVR) exposure is involved in the pathogenesis of systemic lupus erythematosus (SLE), and is known to affect clinical outcomes in patients with SLE. Educating patients with SLE about the importance of avoiding UVR is an essential therapeutic intervention. In this review, the authors provide background information on the UV spectrum and the important biological effects of UVR, and discuss UVR exposure in the setting of SLE. The important properties of available sunscreen ingredients are also reviewed, with particular emphasis on appropriate UVA protection and recommendations for patient counseling.

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