Prostate specific antigen at the initial diagnosis of metastasis to bone in patients after radical prostatectomy.
Loeb S, Makarov DV, Schaeffer EM et al.
Editor’s note: The authors of this study retrospectively investigated a cohort of men who underwent radical prostatectomy (RP) by multiple surgeons at their institution. They identified patients who underwent surgery between 1982 and 2008, and later demonstrated the development of metastasis in the bone. In particular, they examined the prostate-specific antigen (PSA) distribution at the time of bone scan conversion according to the time from RP to metastasis.