Infliximab, azathioprine, or combination therapy for Crohn’s disease
SONIC (Study of Biologic and Immunomodulator-Naïve Patients in Crohn’s Disease) was a randomized, double-blind, 30-week trial evaluating the efficacy of infliximab monotherapy, azathioprine monotherapy, and a combination of the two drugs in moderate-to-severe Crohn’s disease patients naïve to
immunosuppressive or biological therapy.
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