Paper of the Month - May, 2011

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Genetics in twins with Crohn’s disease: less pronounced than previously believed?

Halfvarson J.
A number of twin studies have previously been conducted to estimate concordance rates and thus the genetic contribution in IBD. However, many of these studies have had methodological limitations, including the lack of standardization according to age. This author aimed to establish concordance rates for Crohn’s disease and ulcerative colitis, and also to evaluate phenotypes in concordant and discordant twin pairs.


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