Early symptomatic response and mucosal healing with mesalazine rectal suspension therapy in active distal ulcerative colitis – additional results from two controlled studies
Sandborn WJ, Hanauer S, Lichtenstein GR et al.
In this analysis of data from two previous clinical trials, the effect of mesalazine enemas in active distal ulcerative colitis was determined. Although the rates of mucosal healing at 6 weeks differed between the two studies, both demonstrated significant rapid improvements in rectal bleeding with mesalazine enemas, with a median time to cessation of rectal bleeding of 8 days.