Crohn’s disease is a chronic, relapsing, inflammatory disorder of unknown etiology that can involve the entire gastrointestinal tract. Crohn’s disease affects approximately 500 000 patients in the US and frequently requires both medical and surgical management [1]. Approximately 80% of Crohn’s disease patients will require surgery in their lifetime [2]. While surgery removes the diseased intestine, it is not curative and recurrence is common. In Crohn’s disease patients who have undergone a resection due to disease, the endoscopic recurrence rate of disease at 1 year is 70–90% [3,4]. A much smaller proportion of patients have clinical recurrence of disease at 1 year – as low as 20–37% [3,4].