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Produced and published by Remedica Medical Education and Publishing Limited.
With the increased use of immunosuppressive and biological agents for the treatment of IBD, the risk of serious side effects, especially lymphoma, has become a major concern for clinicians managing patients with Crohn’s disease and ulcerative colitis.
The advent of genome-wide association scanning has revolutionized the search for genetic loci associated with IBD. Recent meta-analyses from the International IBD Genetics Consortium have increased the number of confirmed IBD susceptibility genes and loci to 100.
Several radiological and endoscopic techniques are now available for the study of IBD; each technique is characterized by a distinct profile of advantages and disadvantages. In everyday practice, the choice of the technique to be used depends upon its availability and careful evaluation of its diagnostic accuracy, clinical usefulness, safety, and cost.