May 24, 2012

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Noninvasive Imaging in  Crohn’s Disease Assessment  

Emma Calabrese, MD, PhD, and Francesco Pallone, MD

Currently, the incidence of IBD is increasing worldwide, especially in Northern Europe and North America. The diagnosis of IBD with its two main sub-forms, Crohn’s disease and ulcerative colitis (UC), is based on clinical, endoscopic, radiological, and histological criteria. The main innovations in diagnostic technologies include the development of more sophisticated endoscopic and noninvasive imaging techniques with the aim of improving the identification of complications. Noninvasive tests for the diagnosis and follow-up of IBD have gained increasing attention. Rapid and inexpensive noninvasive tests that are sensitive, specific, and simple to perform and evaluate are necessary to prevent patient discomfort, delays in diagnosis, and unnecessary costs. These newer modalities, which are rapidly changing IBD diagnostic and management algorithms, are described in this review.

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Ultrasonography in Rheumatic Diseases: Can We Do Without It?

Ahmed S Zayat, MBBCh, MSc, MRCP¹, Richard J Wakefield, BM, MD, FRCP¹, Philip G Conaghan, MBBS, PhD, FRACP, FRCP^1,2, and Paul Emery, MA, MD, FRCP¹

International Journal of Advances in Rheumatology

Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology

Buonocore S, Ahern PP, Uhlig HH et al.

Inflammatory Bowel Disease Monitor

Mesenchymal Stromal Cells in Crohn’s Disease

Marjolijn Duijvestein, MD, and Daniel W Hommes, MD, PhD

Inflammatory Bowel Disease Monitor

Management of Severe Pediatric Ulcerative Colitis

Richard K Russell, PhD¹, and Dan Turner, MD, PhD²

Inflammatory Bowel Disease Monitor

Surgical Management of Stricturing Crohn’s Disease

Alex Tzivanakis MB, BS, BSc, MRCS, and Bruce George, MB, MS, BSc, FRCS

Inflammatory Bowel Disease Monitor

LATEST ARTICLES

Leading Articles
- Lymphoma and IBD:  What is the Actual Risk? 
  
  Guillaume Pineton de Chambrun, MD¹, Laurent Peyrin-Biroulet, MD², Bénédicte De Vroey, MD¹, and Jean-Frédéric Colombel, MD¹
  
  ¹Clinique des Maladies de l’Appareil Digestif et de la Nutrition, Hôpital Claude Huriez, CHRU Lille, and²Service d’Hépato-Gastroentérologie, CHU de Nancy, Vandœuvre-lès-Nancy, France
  
  With the increased use of immunosuppressive and biological agents for the treatment of IBD, the risk of serious side effects, especially lymphoma, has become a major concern for clinicians managing patients with Crohn’s disease and ulcerative colitis.
- 100 Genes for IBD... Whatever Next!? 
  
  James C Lee, MD^1,2, and Miles Parkes, MD²
  
  ¹Cambridge Institute for Medical Research, University of Cambridge, and ²Department of Gastroenterology, Addenbrooke’s Hospital, Cambridge, UK
  
  The advent of genome-wide association scanning has revolutionized the search for genetic loci associated with IBD. Recent meta-analyses from the International IBD Genetics Consortium have increased the number of confirmed IBD susceptibility genes and loci to 100.
- Noninvasive Imaging in  Crohn’s Disease Assessment  
  
  Emma Calabrese, MD, PhD, and Francesco Pallone, MD
  
  Cattedra di Gastroenterologia, Dipartimento di Medicina, Università di Roma “Tor Vergata”, Rome, Italy
  
  Several radiological and endoscopic techniques are now available for the study of IBD; each technique is characterized by a distinct profile of advantages and disadvantages. In everyday practice, the choice of the technique to be used depends upon its availability and careful evaluation of its diagnostic accuracy, clinical usefulness, safety, and cost.
Clinical Reviews
Meeting Reports
- Report from United European Gastroenterology Week 2010 
  
  Anne Christine W Vos, MD, and Marjolijn Duijvestein, MD, PhD
  
  Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, The Netherlands
  
  More than 14 000 participants attended the 18th United European Gastroenterology Week (UEGW) in sunny Barcelona, Spain, from October 23–27, 2010. The annual UEGW is a joint congress of four organizations: the United European Gastroenterology Federation, the World Gastroenterology Organization, the World Organization of Digestive Endoscopy (OMED), and the British Society of Gastroenterology.

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Produced and published by Remedica Medical Education and Publishing Limited.

May 24, 2012

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