February 23, 2012

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Treatment Strategies

Gainsbury ML, Chu DI, Howard LA et al. J Gastrointest Surg 2011;15:397–403.

These authors attempted to address the controversy surrounding the risk of surgical complications associated with preoperative infliximab use in medically refractory ulcerative colitis patients. No significant differences were identified in terms on infectious or non-infectious complications between an infliximab and non-infliximab-treated group, post-surgery. However, this study was limited by its retrospective design and the fact that all patients were operated on by a single surgeon.

There is considerable controversy as to whether preoperative use of infliximab increases the risk of surgical complications after proctocolectomy with ileal pouch–anal anastomosis (IPAA), which is currently the surgical procedure of choice for ulcerative colitis (UC) patients who are refractory to medical therapy.

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LATEST ARTICLES

Leading Articles
- Characterizing the Microbiota in IBD
  
  Richard Hansen, MB ChB^1,2, Emad El-Omar, MD¹, and Georgina L Hold, PhD¹
  
  ¹Gastrointestinal Research Group, Division of Applied Medicine, University of Aberdeen; ²Child Health, University of Aberdeen, Royal Aberdeen Children’s Hospital, Foresterhill, Aberdeen, UK
  
  The genetic revolution in IBD has resulted in the detection of 99 susceptibility loci and moved the focus of research to the host–environment interface and the role of the innate immune system. The most important element of this interface is thought to be the microbial residents of the gastrointestinal (GI) tract, the so-called microbiota.
- Confocal Laser Endomicroscopy for IBD Assessment: An Update
  
  Helmut Neumann, MD, PhD¹, Raja Atreya, MD, PhD¹, Michael Vieth, MD, PhD²,  and Markus F Neurath, MD, PhD¹
  
  ¹Department of Medicine I, University of Erlangen–Nuremberg, Erlangen, and ²Institute of Pathology, Klinikum Bayreuth, Bayreuth, Germany
  
  Advanced endoscopic imaging with virtual histology has become clinical reality since the introduction of confocal laser endomicroscopy (CLE) in 2004. In the meantime, various studies have shown the explicit potential of CLE for the diagnosis and characterization of different disease entities, including IBD.
- Is Diet Involved in the Etiology of Ulcerative Colitis and Crohn’s Disease? A Review of the Experimental and Epidemiological Literature 
  
  Punyanganie de Silva, MBBS, MRCP(UK)¹, Elizabeth K Lund, PhD²,  Simon Chan, MB BChir, MRCP, PhD^1,3, and Andrew R Hart, MD^1,3
  
  ¹Norfolk & Norwich University Hospital NHS Trust, ²School of Biological Sciences, University of East Anglia, and³Norwich Medical School, University of East Anglia, Norwich, UK
  
  The increasing adoption of a “Western diet” and the differences in food intake between low- and high-risk areas for IBD suggest that diet may be an important etiological factor.
Clinical Reviews
Meeting Reports
- Digestive Disease Week 2011:  An Update on IBD Basic Science 
  
  Atsushi Sakuraba, MD
  
  Section of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Chicago, Chicago, IL, USA
  
  Digestive Disease Week (DDW) 2011 brought together both clinicians and basic scientists to present and discuss novel aspects of gastrointestinal and liver diseases. The current report summarizes the highlights of mostly unpublished basic research in the field of IBD presented at the meeting.
- Digestive Disease Week 2011:  An Update on IBD Clinical Research 
  
  Frank Hoentjen, MD, PhD
  
  Inflammatory Bowel Disease Center, University of Chicago, Chicago, IL, USA
  
  Digestive Disease Week (DDW) 2011 was held from May 7–10, 2011, in Chicago, IL, USA. IBD, in particular biological therapy in IBD, was a popular topic, and these sessions were well attended. This report will summarize the most important clinical findings in IBD research presented at this year’s meeting.

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(Volume 12 Issue 1 / Leading Articles)
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(Volume 09 Issue 4 / Leading Articles)
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(Volume 08 Issue 4 / Leading Articles)
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(Volume 11 Issue 3 / Leading Articles)

British Society of Gastroenterology Annual Meeting 2011
(Volume 11 Issue 4 / Meeting Reports)
1st British Society of Gastroenterology Supraregional Meeting 
(Volume 12 Issue 2 / Meeting Reports)

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February 23, 2012

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Produced and published by Remedica Medical Education and Publishing Limited.

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Inflammatory Bowel Disease Monitor

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Treatment Strategies

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LATEST ARTICLES

Leading Articles

Characterizing the Microbiota in IBD

Richard Hansen, MB ChB^1,2, Emad El-Omar, MD¹, and Georgina L Hold, PhD¹

Confocal Laser Endomicroscopy for IBD Assessment: An Update

Helmut Neumann, MD, PhD¹, Raja Atreya, MD, PhD¹, Michael Vieth, MD, PhD²,  and Markus F Neurath, MD, PhD¹

Is Diet Involved in the Etiology of Ulcerative Colitis and Crohn’s Disease? A Review of the Experimental and Epidemiological Literature

Punyanganie de Silva, MBBS, MRCP(UK)¹, Elizabeth K Lund, PhD²,  Simon Chan, MB BChir, MRCP, PhD^1,3, and Andrew R Hart, MD^1,3

Clinical Reviews

Pathogenesis

Pediatric IBD

Pregnancy Outcomes

Epidemiology

Diagnostic Imaging

Gut Microbiota

Treatment Strategies

Miscellaneous

Meeting Reports

Digestive Disease Week 2011:  An Update on IBD Basic Science

Atsushi Sakuraba, MD

Digestive Disease Week 2011:  An Update on IBD Clinical Research

Frank Hoentjen, MD, PhD

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February 23, 2012 CLOSE To subscribe to updates from this journal click Confirm. Updates will be displayed in your default RSS reader. Produced and published by Remedica Medical Education and Publishing Limited. » Contact us

Treatment Strategies

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LATEST ARTICLES

Leading Articles

Richard Hansen, MB ChB1,2, Emad El-Omar, MD1, and Georgina L Hold, PhD1

Helmut Neumann, MD, PhD1, Raja Atreya, MD, PhD1, Michael Vieth, MD, PhD2, and Markus F Neurath, MD, PhD1

Punyanganie de Silva, MBBS, MRCP(UK)1, Elizabeth K Lund, PhD2, Simon Chan, MB BChir, MRCP, PhD1,3, and Andrew R Hart, MD1,3

Clinical Reviews

Meeting Reports

Atsushi Sakuraba, MD

Frank Hoentjen, MD, PhD

Our most popular articles

February 23, 2012

CLOSE

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Produced and published by Remedica Medical Education and Publishing Limited.

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Richard Hansen, MB ChB^1,2, Emad El-Omar, MD¹, and Georgina L Hold, PhD¹

Helmut Neumann, MD, PhD¹, Raja Atreya, MD, PhD¹, Michael Vieth, MD, PhD²,  and Markus F Neurath, MD, PhD¹

Punyanganie de Silva, MBBS, MRCP(UK)¹, Elizabeth K Lund, PhD²,  Simon Chan, MB BChir, MRCP, PhD^1,3, and Andrew R Hart, MD^1,3