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Paper of the Month - July, 2011

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The impact of four dynamic, goal-steered treatment strategies on the 5-year outcomes of rheumatoid arthritis patients in the BeSt study

Klarenbeek NB, Güler-Yüksel M, van der Kooij SM et al.

Current guidelines indicate that the treatment of rheumatoid arthritis should be dynamic, based upon predefined treatment goals. In a 5-year follow-up of the BeSt (Behandel-Strategieën) study participants, it was demonstrated that dynamic treatment based upon continuously adapting pharmacological treatment aiming at achieving low disease activity, resulted in a remission rate of 48%. In approximately one out of six patients, drug-free remission was achieved.

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Association between biologic therapies for chronic plaque psoriasis and cardiovascular events: a meta-analysis of randomized controlled trials - March, 2012
Atacicept in patients with rheumatoid arthritis and an inadequate response to tumor necrosis factor antagonist therapy: results of a Phase II, randomized, placebo-controlled, dose-finding trial - February, 2012
Association between disease modifying antirheumatic drugs and diabetes risk in patients with rheumatoid arthritis and psoriasis - January, 2012
Bone edema on magnetic resonance imaging is an independent predictor of rheumatoid arthritis development in patients with early undifferentiated arthritis - December, 2011
Acquisition of the rheumatoid arthritis HLA shared epitope through microchimerism - November, 2011
The lifetime risk of adult-onset rheumatoid arthritis and other inflammatory autoimmune rheumatic diseases - October, 2011
MRI in early rheumatoid arthritis: synovitis and bone marrow oedema are independent predictors of subsequent radiographic progression - September, 2011
Efficacy and safety of anakinra therapy in pediatric and adult patients with the autoinflammatory Muckle–Wells syndrome - August, 2011
The impact of four dynamic, goal-steered treatment strategies on the 5-year outcomes of rheumatoid arthritis patients in the BeSt study - July, 2011
Rheumatoid arthritis-interstitial lung disease-associated mortality - June, 2011
Impact of obesity and knee osteoarthritis on morbidity and mortality in older Americans - May, 2011
The presence or absence of antibodies to infliximab or adalimumab determines the outcome of switching to etanercept - April, 2011
Beneficial effect of 1-year etanercept treatment on the lipid profile in responding patients with rheumatoid arthritis: the ETRA study - March, 2011
Musculoskeletal pain is associated with very low levels of vitamin D in men: results from the European Male Ageing Study - February, 2011
Individual susceptibility to periprosthetic osteolysis is associated with altered patterns of innate immune gene expression in response to pro-inflammatory stimuli - January, 2011
Rheumatologists’ awareness of and screening practices for hepatitis B virus infection prior to initiating immunomodulatory therapy - December, 2010
Rituximab versus cyclophosphamide in ANCA-associated renal vasculitis - November, 2010
Inflammatory markers in patients with coronary artery disease with and without inflammatory rheumatic disease - October, 2010
Statin use in rheumatoid arthritis in relation to actual cardiovascular risk: evidence for substantial undertreatment of lipid-associated cardiovascular risk? - September, 2010
Efficacy and safety of anti-TNF therapies in psoriatic arthritis: an observational study from the British Society for Rheumatology Biologics Register - August, 2010
The role of dynamic contrastenhanced MRI in the differential diagnosis of psoriatic and rheumatoid arthritis - July, 2010
Postpartum onset of rheumatoid arthritis and other chronic arthritides: results from a patient register linked to a medical birth registry - June, 2010
Patient preferences in the choice of anti-TNF therapies in rheumatoid arthritis. Results from a questionnaire survey (RIVIERA study) - May, 2010
Comparison of two etanercept regimens for treatment of psoriasis and psoriatic arthritis: PRESTA randomised double blind multicentre trial - April, 2010
Involvement of MAPKs and NFkappaB in tumor necrosis factor alpha-induced vascular cell adhesion molecule 1 expression in human rheumatoid arthritis synovial fibroblasts - March, 2010
DAS-driven therapy versus routine care in patients with recent-onset active rheumatoid arthritis - February, 2010
The time has come to limit the placebo period in rheumatoid arthritis trials to 3 months: a systematic comparison of 3- and 6-month response rates in trials of biological agents - January, 2010
The good initial response to therapy with a combination of traditional disease-modifying antirheumatic drugs is sustained over time: the eleven-year results of the Finnish rheumatoid arthritis combination therapy trial - 2009
Zoledronic acid and risedronate in the prevention and treatment of glucocorticoid-induced osteoporosis (HORIZON ): a multicentre, double-blind, double-dummy, randomised controlled trial - 2009
Value of anti-modified citrullinated vimentin and third-generation anti-cyclic citrullinated peptide compared with second-generation anti-cyclic citrullinated peptide and rheumatoid factor in predicting disease outcome in undifferentiated arthritis and rheumatoid arthritis - 2009

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Produced and published by Remedica Medical Education and Publishing Limited.

May 24, 2012 CLOSE To subscribe to updates from this journal click Confirm. Updates will be displayed in your default RSS reader. Produced and published by Remedica Medical Education and Publishing Limited. » Contact us

International Journal of Advances in Rheumatology » Advanced search