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The Journal of Invasive Fungal Infections

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Latest Issue

Volume 4 Issue 1

Leading ArticlesClick to expand
- Calcineurin Pathway Inhibition: A Novel Antifungal Strategy
  
  in The Journal of Invasive Fungal Infections (Volume 4 Issue 1 / Leading Articles)
  
  William J Steinbach, MD
  
  Division of Pediatric Infectious Diseases, Department of Pediatrics, and Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC, USA
  
  As the burden of invasive fungal infection increases, newer strategies for the development of antifungal agents are needed. Numerous studies on the existing classes of available antifungals have not yielded optimal treatments, suggesting that a novel and unique approach is warranted. The calcineurin pathway is a stress-response mechanism employed by fungi.
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- Immunotherapy for Invasive Fungal Infections
  
  in The Journal of Invasive Fungal Infections (Volume 4 Issue 1 / Leading Articles)
  
  Ganapathi I Parameswaran, MD¹, and Brahm H Segal, MD, FACP, FIDSA^1,2
  
  ¹Division of Infectious Diseases; and ²Roswell Park Cancer Institute, State University of New York–Buffalo, Buffalo, NY, USA.
  
  Invasive fungal infections are important causes of morbidity and mortality in the highly immunocompromised population. Different host factors predispose to infections by specific fungal pathogens. Because of this knowledge of innate and antigen-driven immunity against fungal pathogens, it is important to develop immune-based therapies.
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- Treatment of Invasive Aspergillosis: A Systematic Review of Randomized Clinical Trials
  
  in The Journal of Invasive Fungal Infections (Volume 4 Issue 1 / Leading Articles)
  
  Alessandro C Pasqualotto, MD, PhD¹, and Arnaldo L Colombo, MD, PhD²
  
  ¹Infection Control Department, Santa Casa Complexo Hospitalar, Porto Alegre; and ²Special Mycology Laboratory, Division of Infectious Diseases, Federal University of São Paulo (UNIFESP), São Paulo, Brazil
  
  Invasive aspergillosis (IA) has emerged as an important medical problem in recent years. Despite advances in the diagnosis of this condition, as well as the availability of better-tolerated antifungal drugs, the mortality rates associated with IA have remained very high. Although several antifungal drugs are known to have potent activity against Aspergillus spp., data from clinical trials remain limited.
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Clinical ReviewsClick to expand
- Risk
  
  in The Journal of Invasive Fungal Infections (Volume 4 Issue 1 / Clinical Reviews)
  
  » Read more
- Pathogenesis
  
  in The Journal of Invasive Fungal Infections (Volume 4 Issue 1 / Clinical Reviews)
  
  » Read more
- Antifungal Immunity
  
  in The Journal of Invasive Fungal Infections (Volume 4 Issue 1 / Clinical Reviews)
  
  » Read more
- Treatment Strategies
  
  in The Journal of Invasive Fungal Infections (Volume 4 Issue 1 / Clinical Reviews)
  
  » Read more
- Diagnosis and Assessment
  
  in The Journal of Invasive Fungal Infections (Volume 4 Issue 1 / Clinical Reviews)
  
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- Therapeutics Research
  
  in The Journal of Invasive Fungal Infections (Volume 4 Issue 1 / Clinical Reviews)
  
  » Read more
- Drug Resistance
  
  in The Journal of Invasive Fungal Infections (Volume 4 Issue 1 / Clinical Reviews)
  
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- Prognosis
  
  in The Journal of Invasive Fungal Infections (Volume 4 Issue 1 / Clinical Reviews)
  
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Meeting ReportsClick to expand
- Report from the 4th Trends in Medical Mycology Meeting (TIMM-4)
  
  in The Journal of Invasive Fungal Infections (Volume 4 Issue 1 / Meeting Reports)
  
  Argiris Symeonidis, MD, PhD¹, and Jenny Bryan, BSc²
  
  University of Patras Medical School, Patras, Greece; and ²Medical Writer, London, UK
  
  Although once the remit of only mycologists, hematologists, and oncologists, invasive fungal infections (IFI) are rapidly moving onto the radar of a much wider range of clinicians since chronic conditions, such as diabetes mellitus, asthma, chronic obstructive pulmonary disease, cystic fibrosis, congenital immunodeficiencies, and various diseases associated with treatment-related immunosuppression are now well recognized as risk factors.
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© Remedica 2012. All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording, or otherwise without the prior permission of the copyright owners. While every effort is made by the publishers and editorial board to see that no inaccurate or misleading data, opinions, or statements appear in this journal, they wish to make it clear that the material contained in the publication represents a summary of the independent evaluations and opinions of the authors and contributors. As a consequence, the board, publishers, and any supporting company accept no responsibility for the consequences of any such inaccurate or misleading data or statements. Neither do they endorse the content of the publication or the use of any drug or device in a way that lies outside its current licensed application in any territory. For detailed information on any drugs or devices discussed in this publication, readers are advised to consult the manufacturer’s prescribing information.

Produced and published by Remedica Medical Education and Publishing Limited.

February 08, 2012 CLOSE To subscribe to updates from this journal click Confirm. Updates will be displayed in your default RSS reader. Produced and published by Remedica Medical Education and Publishing Limited. » Contact us

Latest Issue

Volume 4 Issue 1

Leading Articles

William J Steinbach, MD

Ganapathi I Parameswaran, MD1, and Brahm H Segal, MD, FACP, FIDSA1,2

Alessandro C Pasqualotto, MD, PhD1, and Arnaldo L Colombo, MD, PhD2

Clinical Reviews

Meeting Reports

Argiris Symeonidis, MD, PhD1, and Jenny Bryan, BSc2

Volume 4 Issue 1

Leading ArticlesClick to expand

in The Journal of Invasive Fungal Infections (Volume 4 Issue 1 / Leading Articles)

William J Steinbach, MD

in The Journal of Invasive Fungal Infections (Volume 4 Issue 1 / Leading Articles)

Ganapathi I Parameswaran, MD1, and Brahm H Segal, MD, FACP, FIDSA1,2

in The Journal of Invasive Fungal Infections (Volume 4 Issue 1 / Leading Articles)

Alessandro C Pasqualotto, MD, PhD1, and Arnaldo L Colombo, MD, PhD2

Clinical ReviewsClick to expand

in The Journal of Invasive Fungal Infections (Volume 4 Issue 1 / Clinical Reviews)

in The Journal of Invasive Fungal Infections (Volume 4 Issue 1 / Clinical Reviews)

in The Journal of Invasive Fungal Infections (Volume 4 Issue 1 / Clinical Reviews)

in The Journal of Invasive Fungal Infections (Volume 4 Issue 1 / Clinical Reviews)

in The Journal of Invasive Fungal Infections (Volume 4 Issue 1 / Clinical Reviews)

in The Journal of Invasive Fungal Infections (Volume 4 Issue 1 / Clinical Reviews)

in The Journal of Invasive Fungal Infections (Volume 4 Issue 1 / Clinical Reviews)

in The Journal of Invasive Fungal Infections (Volume 4 Issue 1 / Clinical Reviews)

Meeting ReportsClick to expand

in The Journal of Invasive Fungal Infections (Volume 4 Issue 1 / Meeting Reports)

Argiris Symeonidis, MD, PhD1, and Jenny Bryan, BSc2

READER POLL

Post Page On

SUBMIT AN ARTICLE

February 08, 2012

CLOSE

To subscribe to updates from this journal click Confirm. Updates will be displayed in your default RSS reader.

Produced and published by Remedica Medical Education and Publishing Limited.

» Contact us

Ganapathi I Parameswaran, MD¹, and Brahm H Segal, MD, FACP, FIDSA^1,2

Alessandro C Pasqualotto, MD, PhD¹, and Arnaldo L Colombo, MD, PhD²

Argiris Symeonidis, MD, PhD¹, and Jenny Bryan, BSc²

Ganapathi I Parameswaran, MD¹, and Brahm H Segal, MD, FACP, FIDSA^1,2

Alessandro C Pasqualotto, MD, PhD¹, and Arnaldo L Colombo, MD, PhD²

Argiris Symeonidis, MD, PhD¹, and Jenny Bryan, BSc²