Armenian SH, Nash KA, Kapoor N et al.
J Pediatr Hematol Oncol 2009;31:920–6.
In this study, 68 pediatric patients at high risk of invasive aspergillosis (IA) were prospectively monitored with twice-weekly serum galactomannan (GM) testing and blood polymerase chain reaction (PCR) for Aspergillus spp.
This approach was not found to improve the speed and accuracy of diagnosis of IA in this patient population.
It is important to reliably and promptly establish the diagnosis of invasive aspergillosis (IA) in high-risk patients in order to improve the outcome of these infections. Serum galactomannan (GM) testing and blood polymerase chain reaction (PCR) are useful tools for diagnosis that need to be evaluated in high-risk pediatric patients.