The current understanding of the fungal biofilm is that it is a complex community of microorganisms capable of surviving and thriving in a multitude of environments. Its ability to adhere and colonize on a number of different substrates including biomaterials and implantable devices can impact healthcare delivery. The tenacity of these microbial complexes does not lend itself to eradication by traditional pharmacological therapies. Biofilm resistance continues to affect patient care and healthcare costs. This review provides an overview of fungal biofilms from the historical perspective of early studies to current concepts and future directions in biofilm research. J Invasive Fungal Infect 2011;5(2):37–42.