Paper of the Month - Volume 3 Issue 1

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Diagnosis and Assessment

Can MM, Kaymaz C, Tanboga IH et al.

Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital, Istanbul, Turkey.

 Clin Nucl Med 2011;36:743–8.

Editor’s note: The authors of this study used 18F-fluorodeoxyglucose (FDG) uptake on positron emission tomography (PET) scanning to demonstrate that relative right ventricular (RV) glucose metabolism is increased in the pressure-overloaded RV in various populations with pulmonary arterial hypertension (PAH). Further correlations are shown between relative FDG uptake and the hemodynamic severity of PAH and echocardiographic markers of RV dysfunction. This is, however, a relatively small cross-sectional study with no outcome data, the PAH population is non-homogenous, and the mean PA pressure (mPAP) of 74 mmHg in the study population provides little insight into the early RV response to pressure overload.



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